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Careers at Entrada

As Entradans, we exist to help patients, and their families live better lives.

Our Values

Together, we are fiercely committed to advancing science into transformative medicines that will change lives. Innovation isn’t easy, and we’re up for the challenge. Are you?

We have a mission-driven culture where collaboration, intellectual curiosity and a sense of discovery extend beyond the bench to everything we do. We strive for this every day and in every role, so that each Entradan can grow and fully contribute to our community.

We are building a company culture where everyone can belong, contribute and grow. Whether you’re tackling new challenges or learning on the job, your successes are celebrated, and hurdles aren’t faced alone.

  • Humanity

    We genuinely care about patients and about one another.

  • Tenacity

    We're relentless and persistent in the pursuit of developing therapies for patients.

  • Creativity

    We're creative problem solvers.

  • Collaboration

    We're more than the sum of our parts.

  • Curiosity

    We've got a growth mindset.

Our Comprehensive Benefits

Entrada takes care of you so you can focus on our science and mission; our perks and benefits are designed to meet your needs regardless of what season of life you are in.

Wellness Stipend

Wellness Stipend

We invest in your well-being – whatever that looks like.

Entrada offers a $500 wellness stipend for you to spend however you’d like – whether it’s to fund art supplies, a gym membership or a manicure!

Team Events

Team Events

Do you like dumplings?

We host countless company-sponsored social events to encourage connection, with our annual dumpling making event to celebrate Lunar New Year being a team favorite.

Parental Leave

Parental Leave

Kids are the future – we support taking care of yours.

We’re proud to provide extensive, gender-inclusive parental leave so you have the time and space to connect with your growing family.

Commuter Benefits

Commuter Benefits

You go the extra mile, so we return the favor. 

Our local Entradans receive up to $325 to cover commute expenses – be it gas, bus fares or a train ticket.

Holistic Health Support

Holistic Health Support

Prioritizing your health, holistically.

Whether it’s contributing to your Health Savings Account or offering mental wellness and financial coaching services, Entrada supports all of your health needs.

Education Reimbursement

Education Reimbursement

There’s always more to learn. 

We believe that knowledge is power, so we aim to support your long-term career journey with education reimbursement.

Milestone Celebrations

Milestone Celebrations

We celebrate your wins – from the big to the small.

Whether it’s receiving a Milestone Gift or a shoutout from your manager, you are celebrated for your contributions.

Flexible Working Model

Flexible Working Model

Get the job done your way – wherever that is. 

We offer role-dependent remote options – as long as you are delivering impact, you choose where you work best.

In-office Fuel

In-office Fuel

Hungry for more?

We offer fully subsidized lunches, snacks, drinks and treats to fuel you and your work.

Excited by what you see?

We pride ourselves on offering competitive benefits that empower our employees and reflect the value of their contributions – that's why we openly share the details of our comprehensive benefits package!

What Sets Us Apart:

Since our inception, we have worked to build a high-performing, inclusive and diverse team, which is a core element of our culture.

  • 56% Identify as women
  • 52% Asian, Hispanic, Latino, Black, or African American
  • 62% Of our Senior Leadership Team and Board is made up of women and minorities

Self-reported, as of March 2024.

Entradans are committed to making a difference in the lives of patients, their families and care partners. We believe that by embracing differences, we have a unique advantage in challenging the status quo to apply innovative thinking to long-existing medical challenges.

We clearly think working at Entrada is pretty great. But we're not the only ones!

We clearly think working at Entrada is pretty great. But we're not the only ones!

Watch What We’re Up To

Inside Our Headquarters
Chinese New Year
Chinese New Year EPIC Event

We are each unique in our experiences and backgrounds but unified in our approach – with each Entradan bringing a genuine care for patients and community. We proudly offer multiple Employee Resource Groups (ERGs) in an effort to foster deeper connections and encourage a sense of belonging for all Entradans. 

Through the Entrada Planning & Impact Committee (EPIC), Entradans are empowered to organize the events they want to see within our community – whether it’s volunteering opportunities, holiday celebrations or cultural events honoring our team’s diverse backgrounds and traditions.

Hispanic Heritage Month
Hispanic Heritage Month Panel Discussion
“Embrace”
“Embrace” Group Visit

Hear from Our Entradans

Arianna Bonilla

Coming from academia, I haven’t always had the opportunity to interact with the patient community.

At Entrada, we regularly host families affected by the diseases we’re targeting, and it’s incredibly motivating to step back from the bench and see the direct impact of our work.”

Arianna Bonilla
Senior Research Associate, In Vitro Pharmacology
Sandeep Basnet

When you come in to work each day, you can really feel Entrada’s commitment to collaboration come to life. 

As Head of IT, I get to work cross-functionally with every department in the Company, so collaboration is key. Everyone always steps up to achieve common goals, which is what sets Entrada apart from the rest for me.”

Sandeep Basnet
Head of Information Technology
Haoming Liu, PhD

Something that I find special about Entrada is that I not only take pride in the work I do,

but I feel that the Company truly values my contributions because my research helps to advance our shared mission. That is pretty rewarding – especially as a scientist, to know that what you do every day matters.”

Haoming Liu, PhD
Senior Scientist II, Discovery Biology

Picture Yourself at Entrada

Your Lifeat Entrada

Your Life
at Entrada

Entrada takes care of you so you can focus on our shared mission; our benefits are designed to meet your needs, regardless of what season of life you are in.

Your Careerat Entrada

Your Career
at Entrada

How could tuition reimbursement, diverse trainings and strong mentorship help you develop? Entrada invests in every stage of career development because we want our employees to expand their skills, maximize their potential and do their best work.

Your Discoveriesat Entrada

Your Discoveries
at Entrada

We’re united by a shared sense of urgency and passion. Together, we can advance science that solves fundamental problems in the industry.

Your Contributionsat Entrada

Your Contributions
at Entrada

Different perspectives fuel innovation. What unique experiences do you bring to the table and how can we build something better and different, together?

Your Communityat Entrada

Your Community
at Entrada

Our culture is award-winning for a reason. We are deliberate about making our culture a place where everyone can belong, contribute and grow. We are proud to have a diverse, high-performing team and we work hard every day to nurture it.

Your Impactat Entrada

Your Impact
at Entrada

We're relentless and persistent in the pursuit of making a difference in the lives of patients and their families. Join us.

Current Openings

Please be aware of fraudulent hiring outreach and job offers. Entrada Therapeutics will never initiate contact with applicants via text message nor conduct interviews through messaging apps, freelance sites, or social media platforms (Facebook, Telegram, Instagram, Skype, WhatsApp, etc.). Entrada team members will never request any sensitive or financial information, such as banking account numbers, social security, or driver’s license numbers, nor would we charge job seekers fees or request you make purchases throughout the recruitment process. The only legitimate business email domain we use is @entradatx.com and the Company’s team members will never use a Gmail or another personal email address to contact potential applicants.

Senior Medical Director, Clinical Development

Boston, MA

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. 

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA- and protein-based programs for the potential treatment of neuromuscular and ocular diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You are a versatile, self-motivated team player who looks forward to rolling up your sleeves to drive efficient clinical development and delivery of drugs for devastating diseases.  You thrive in a fast-paced collaborative environment and can manage multiple projects concurrently.  You excel at building relationships and trust with your key stakeholders, in particular across nonclinical and clinical functions, as well as externally. You know when to step in and lead something and when to offer your support.

The Opportunity

As the Senior Medical Director, reporting directly to the Senior Vice President of Clinical Development, you will work in a cross-functional manner to drive the neuromuscular development programs, from early stages into and through clinical trials.  You will build strategic alliances with external stakeholders, such as KOLs, and support colleagues within Entrada by offering a clinical perspective.

Responsibilities

  • Provide oversight and leadership of clinical program including planning, execution, and completion of clinical trials according to all applicable regulations and guidance, ICH/GCP, and Entrada SOPs.
  • Collaborate closely with internal research team to integrate translational research into development and clinical strategies.
  • Partner with Clinical Operations to ensure all clinical study activities are completed in accordance with applicable regulations and guidance; ICH/GCP, and Entrada SOPs.
  • Review clinical data from all phases of development and assist in generating study reports and publications.
  • Develop and maintain relationships and serve as the main medical liaison with key opinion leaders and Principal Investigators.
  • Represent Entrada in interactions with regulatory agencies.
  • Provide management personnel with timely updates on progress and changes in scope, schedule, and resources as required.
  • Ensure compliance with all applicable regulatory standards related to global clinical trials and interactions with physicians.
  • Develop and maintain professional relationships with academic and community-based study sites involved in clinical development programs.
  • Lead internal and external team members, vendors, and consultants to develop regulatory submission packages, as well as review and evaluate pre-clinical safety data for regulatory submission.
  • Be responsible for the clinical content of all clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, CRF’s, annual IND reports, CSR’s, ISS’s, ISE’s, and clinical expert reports.
  • Organize and present at relevant clinical advisory boards, data monitor committees and medical/scientific meetings, including collaboration in preparation of manuscripts, poster, and/or other scientific communications.
  • Travel nationally and internationally, as needed.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • Physician required (MD/DO or equivalent).
  • 3+ or more years of industry and/or clinical/clinical research experience.
  • Experience with clinical development in Neurology/Neuromuscular disorders.
  • Strong scientific background.
  • Strong project planning, leadership, negotiation, and presentation skills as well as an ability to contribute creative yet practical solutions to problems.
  • Experience with all aspects of management of clinical trials from inception to completion across all phases of development including study design.
  • Experience in communicating/presenting key/complex information to department/functional lead(s)/senior management.
  • Strong knowledge of FDA and ICH regulations.
  • Expert knowledge of Good Clinical Practice (CGP).
  • Ability to multi-task and manage several projects in parallel, paying attention to detail.
  • Ability to forge cross-functional working relationships with internal teams and external project partners, and work in a collaborative manner.
  • Ability to be proactive in identifying issues and hurdles that may hinder the effective implementation of the trial and resolve the issues in a timely fashion.
  • This is a US based remote position, with preference given to local New England based candidates. This role will require a minimum quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA.

What We Offer: Meaningful Work, Fair Rewards, and Real Support

At Entrada Therapeutics, we understand that compensation and total rewards are a major consideration when exploring a new opportunity. We believe in transparency and equity and are committed to sharing salary ranges for every position, along with insight into our compensation philosophy, in accordance with certain state requirements in the United States and fostering a fair and open environment at the onset.

But we also know it is more than just pay. When you join Entrada, you’ll be part of a mission-driven team with access to comprehensive health, dental and vision coverage; life and disability insurance; with a 401(k) match. We pride ourselves on offering competitive benefits that empower our employees and reflect the value of their contributions – offering paid, gender-inclusive parental leave, holistic support for your health and well-being, education reimbursement, discretionary time off and commuting benefits aligned to your working model. If you find yourself working from our office in Boston’s Seaport District, this puts you steps away from some of the best the city has to offer.

“Our approach to compensation is grounded in transparency, equity and performance for the unique contributions each person brings. At Entrada, we know that meaningful work deserves meaningful reward — and we view compensation as one way we show appreciation for the collaboration, curiosity and commitment that drive our mission forward.”

— Kerry Robert, SVP of People

The salary for this opportunity ranges from $328,000 - $387,000. The final base compensation offered will depend on several considerations which include but may not be limited to a candidate’s skills, competencies, experience and other job-related factors permitted by law. The final salary offered may fall outside of this range. #LI-Remote #LI-GG1

Equal Opportunity Employer

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law. 

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

Privacy Statement

Entrada Therapeutics, Inc. (the “Entrada,” “we,” “us,” or “our”) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.