Using our proprietary EEVâ„¢ platform, we are creating a diverse and expanding pipeline of oligonucleotide, antibody and enzyme-based programs. Our lead programs are in neuromuscular diseases, including Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1). Our modular approach supports efficient expansion of development into multiple therapeutic areas, including immunology, oncology and metabolic diseases.
ENTR-601-44 (Exon 44 Skipping Oligonucleotide)
Neuromuscular Disease : Duchenne Muscular Dystrophy
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Preclinical
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Exon 45 Skipping Oligonucleotide
Neuromuscular Disease : Duchenne Muscular Dystrophy
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Preclinical
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ENTR-701 CUG Steric Blocker Oligonucleotide
Neuromuscular Disease : Myotonic Dystrophy Type 1
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Preclinical
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GYS1 Knockdown Oligonucleotide
Neuromuscular Disease : Pompe
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Preclinical
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CD33 Exon 2 Skipping Oligonucleotide
Neurodegenerative Diseases
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Preclinical
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IRF5 Knockdown Oligonucleotide
Inflammatory Diseases
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Preclinical
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β-catenin Degrader Antibody
Solid Tumors
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Discovery
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ENTR-501 Enzyme Replacement
Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
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Preclinical
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