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Intracellular Therapeutics Pipeline

Diverse and Expanding Pipeline of Programs Spanning Discovery and Clinical Development

At Entrada Therapeutics, we are driven to transform the lives of patients by establishing a new class of intracellular therapeutics. We are already developing potential treatments across multiple devastating diseases with a simple and scalable EEV platform designed to translate from preclinical to clinical development.

Learn more about our proprietary EEV™ Platform.

Information is current as of January 8, 2026, updates are made on a quarterly basis.

Duchenne Muscular Dystrophy (DMD)

To learn more about Duchenne muscular dystrophy, visit our DMD Page.

ENTR-601-44 (Exon 44 Skipping Oligonucleotide)

Preclinical 100% complete
Phase 1/2 50% complete
Phase 2/3 0% complete

ENTR-601-45 (Exon 45 Skipping Oligonucleotide)

Preclinical 100% complete
Phase 1/2 25% complete
Phase 2/3 0% complete

ENTR-601-50 (Exon 50 Skipping Oligonucleotide)

Preclinical 100% complete
Phase 1/2 0% complete
Phase 2/3 0% complete

ENTR-601-51 (Exon 51 Skipping Oligonucleotide)

Preclinical 90% complete
Phase 1/2 0% complete
Phase 2/3 0% complete

Myotonic Dystrophy Type 1 (DM1)

To learn more about Myotonic dystrophy type 1, visit our DM1 Page.

VX-670 (Oligonucleotide) 1

Preclinical 100% complete
Phase 1/2 50% complete
Phase 2/3 0% complete

Inherited Retinal Diseases

ENTR-801: USH2A

Preclinical 85% complete
Phase 1/2 0% complete
Phase 2/3 0% complete

Undisclosed Programs

Preclinical 75% complete
Phase 1/2 0% complete
Phase 2/3 0% complete

Pipeline and Platform Expansion

Undisclosed

Preclinical 65% complete
Phase 1/2 0% complete
Phase 2/3 0% complete
References
  1. 1.

    In collaboration with

    Vertex Pharmaceuticals