Our Endosomal Escape Vehicle (EEV™) Platform

Engaging Disease-Causing Targets Previously Considered Inaccessible and Undruggable

about
75
%

~75% of disease-causing targets are located inside cells.1 Yet, most are still considered inaccessible.

about
1-2
%

Only ~1-2% of conventional biological therapeutics reach their intended target.2

about
50
%

Based on preclinical studies, ~HALF of EEV-therapeutics reach their intended target.3

The Challenge with Conventional Intracellular Therapeutics

Delivering a therapy into the cell presents two fundamental challenges:

  1. Getting it inside the cell.
  2. Then, most importantly, avoiding the cell’s natural clearing systems so it can reach the intended target.