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Careers at Entrada

As Entradans, we exist to help patients, and their families live better lives.

Our Values

Together, we are fiercely committed to advancing science into transformative medicines that will change lives. Innovation isn’t easy, and we’re up for the challenge. Are you?

We have a mission-driven culture where collaboration, intellectual curiosity and a sense of discovery extend beyond the bench to everything we do. We strive for this every day and in every role, so that each Entradan can grow and fully contribute to our community.

We are building a company culture where everyone can belong, contribute and grow. Whether you’re tackling new challenges or learning on the job, your successes are celebrated, and hurdles aren’t faced alone.

  • Humanity

    We genuinely care about patients and about one another.

  • Tenacity

    We're relentless and persistent in the pursuit of developing therapies for patients.

  • Creativity

    We're creative problem solvers.

  • Collaboration

    We're more than the sum of our parts.

  • Curiosity

    We've got a growth mindset.

Our Comprehensive Benefits

Entrada takes care of you so you can focus on our science and mission; our perks and benefits are designed to meet your needs regardless of what season of life you are in.

Wellness Stipend

Wellness Stipend

We invest in your well-being – whatever that looks like.

Entrada offers a $500 wellness stipend for you to spend however you’d like – whether it’s to fund art supplies, a gym membership or a manicure!

Team Events

Team Events

Do you like dumplings?

We host countless company-sponsored social events to encourage connection, with our annual dumpling making event to celebrate Lunar New Year being a team favorite.

Parental Leave

Parental Leave

Kids are the future – we support taking care of yours.

We’re proud to provide extensive, gender-inclusive parental leave so you have the time and space to connect with your growing family.

Commuter Benefits

Commuter Benefits

You go the extra mile, so we return the favor. 

Our local Entradans receive up to $325 to cover commute expenses – be it gas, bus fares or a train ticket.

Holistic Health Support

Holistic Health Support

Prioritizing your health, holistically.

Whether it’s contributing to your Health Savings Account or offering mental wellness and financial coaching services, Entrada supports all of your health needs.

Education Reimbursement

Education Reimbursement

There’s always more to learn. 

We believe that knowledge is power, so we aim to support your long-term career journey with education reimbursement.

Milestone Celebrations

Milestone Celebrations

We celebrate your wins – from the big to the small.

Whether it’s receiving a Milestone Gift or a shoutout from your manager, you are celebrated for your contributions.

Flexible Working Model

Flexible Working Model

Get the job done your way – wherever that is. 

We offer role-dependent remote options – as long as you are delivering impact, you choose where you work best.

In-office Fuel

In-office Fuel

Hungry for more?

We offer fully subsidized lunches, snacks, drinks and treats to fuel you and your work.

Excited by what you see?

We pride ourselves on offering competitive benefits that empower our employees and reflect the value of their contributions – that's why we openly share the details of our comprehensive benefits package!

What Sets Us Apart:

Since our inception, we have worked to build a high-performing, inclusive and diverse team, which is a core element of our culture.

  • 56% Identify as women
  • 52% Asian, Hispanic, Latino, Black, or African American
  • 62% Of our Senior Leadership Team and Board is made up of women and minorities

Self-reported, as of March 2024.

Entradans are committed to making a difference in the lives of patients, their families and care partners. We believe that by embracing differences, we have a unique advantage in challenging the status quo to apply innovative thinking to long-existing medical challenges.

We clearly think working at Entrada is pretty great. But we're not the only ones!

We clearly think working at Entrada is pretty great. But we're not the only ones!

Watch What We’re Up To

Inside Our Headquarters
Chinese New Year
Chinese New Year EPIC Event

We are each unique in our experiences and backgrounds but unified in our approach – with each Entradan bringing a genuine care for patients and community. We proudly offer multiple Employee Resource Groups (ERGs) in an effort to foster deeper connections and encourage a sense of belonging for all Entradans. 

Through the Entrada Planning & Impact Committee (EPIC), Entradans are empowered to organize the events they want to see within our community – whether it’s volunteering opportunities, holiday celebrations or cultural events honoring our team’s diverse backgrounds and traditions.

Hispanic Heritage Month
Hispanic Heritage Month Panel Discussion
“Embrace”
“Embrace” Group Visit

Hear from Our Entradans

Arianna Bonilla

Coming from academia, I haven’t always had the opportunity to interact with the patient community.

At Entrada, we regularly host families affected by the diseases we’re targeting, and it’s incredibly motivating to step back from the bench and see the direct impact of our work.”

Arianna Bonilla
Senior Research Associate, In Vitro Pharmacology
Sandeep Basnet

When you come in to work each day, you can really feel Entrada’s commitment to collaboration come to life. 

As Head of IT, I get to work cross-functionally with every department in the Company, so collaboration is key. Everyone always steps up to achieve common goals, which is what sets Entrada apart from the rest for me.”

Sandeep Basnet
Head of Information Technology
Haoming Liu, PhD

Something that I find special about Entrada is that I not only take pride in the work I do,

but I feel that the Company truly values my contributions because my research helps to advance our shared mission. That is pretty rewarding – especially as a scientist, to know that what you do every day matters.”

Haoming Liu, PhD
Senior Scientist II, Discovery Biology

Picture Yourself at Entrada

Your Lifeat Entrada

Your Life
at Entrada

Entrada takes care of you so you can focus on our shared mission; our benefits are designed to meet your needs, regardless of what season of life you are in.

Your Careerat Entrada

Your Career
at Entrada

How could tuition reimbursement, diverse trainings and strong mentorship help you develop? Entrada invests in every stage of career development because we want our employees to expand their skills, maximize their potential and do their best work.

Your Discoveriesat Entrada

Your Discoveries
at Entrada

We’re united by a shared sense of urgency and passion. Together, we can advance science that solves fundamental problems in the industry.

Your Contributionsat Entrada

Your Contributions
at Entrada

Different perspectives fuel innovation. What unique experiences do you bring to the table and how can we build something better and different, together?

Your Communityat Entrada

Your Community
at Entrada

Our culture is award-winning for a reason. We are deliberate about making our culture a place where everyone can belong, contribute and grow. We are proud to have a diverse, high-performing team and we work hard every day to nurture it.

Your Impactat Entrada

Your Impact
at Entrada

We're relentless and persistent in the pursuit of making a difference in the lives of patients and their families. Join us.

Current Openings

Please be aware of fraudulent hiring outreach and job offers. Entrada Therapeutics will never initiate contact with applicants via text message nor conduct interviews through messaging apps, freelance sites, or social media platforms (Facebook, Telegram, Instagram, Skype, WhatsApp, etc.). Entrada team members will never request any sensitive or financial information, such as banking account numbers, social security, or driver’s license numbers, nor would we charge job seekers fees or request you make purchases throughout the recruitment process. The only legitimate business email domain we use is @entradatx.com and the Company’s team members will never use a Gmail or another personal email address to contact potential applicants.

Associate Director, Analytical Development & QC

Boston, MA

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. 

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA- and protein-based programs for the potential treatment of neuromuscular and ocular diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You are motivated, resourceful, and enthusiastic scientist and leader, excited to be a key contributor for the company at a critical stage in its growth trajectory. You enjoy developing and implementing new processes, connecting the dots for Analytical and Quality Control teams. You enjoy a fast-paced environment and juggling competing priorities and are willing to jump in and help wherever it is needed. You follow up and follow through, efficiently connecting problems with solutions. You work successfully in a team environment and have strong interpersonal skills, to effectively build working relationships inside and outside of the company.

The Opportunity

The individual will lead the development, implementation, and improvement of internal QC systems for internal teams and external partners. You will proactively manage QC gap analyses and help lead CDMO partnerships on analytical method transfer and phase-appropriate qualification and validation. You will not be siloed, but rather you will be expected to interact across different functional groups and partner collaboratively.

Responsibilities

  • Lead and manage, in partnership with internal cross-functional teams, QC quality events, such as change controls, deviations, adverse stability trends, OOS/OOT/OOE investigations, root cause analysis, and CAPAs.
  • Partner with internal and external teams to meet timelines and company objectives, including, Non-clinical Development, Quality Assurance, Regulatory, and CRO/CDMOs.
  • Proactively manage QC gap analyses and QC SOP authoring and revisions for continuous improvement.
  • Oversee CDMO for analytical method transfer, phase-appropriate qualification/full validation, reference standard generation and qualification, stability program management and quality control related events.
  • Support CDMO as a technical SME for drug intermediates, DS and DP QC testing activities, ensuring all activities are completed according to established timelines and quality standards.
  • Support CDMO with management and communication of stability pulls and ensure stability testing occurs within specified testing windows to establish/extend DS and DP shelf life based on stability data.
  • Coordinate with internal stakeholders to ensure uninterrupted clinical and commercial supplies.
  • Oversee CDMO to manage reference standard and critical reagent programs, including qualification/requalification, inventory, and bridging activities.
  • Partner with CMC technical SMEs, QA and Regulatory to prepare and review QC related sections of IND, IMPD, NDA/MAA and global regulatory submissions.
  • Provide necessary support information for addressing information requests from regulatory agencies.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • A Ph.D. in Biochemistry, Analytical Chemistry or a related discipline with 6 + years (or 10 + years with a MS. Degree) of analytical and/or quality control experience in a Biotech or Pharmaceutical industry under GMP environment.
  • Strong knowledge in QC principles, concepts, industry practices, and standards, including extensive knowledge of cGMP regulations and guidelines.
  • Experience in characterization, method development, validation, and transfer of non-compendial and compendial analytical methods for oligonucleotides, especially PMO and PPMO, is highly desired.
  • Strong knowledge and hands-on experience in regulatory requirements and guidelines (ICH/FDA/EMA/USP/Ph. Eur.) with respect to the quality control for oligonucleotides.
  • Experience contributing to product quality risk assessments to identify critical quality attributes and developing associated limits/specifications.
  • Excellent communication, both written and verbal, and interpersonal skills.
  • Works independently with minimal supervision and is highly collaborative with other groups.
  • Strong attention to detail and results driven in line with project and team objectives.
  • Ability to handle multiple high priority tasks in parallel to meet organizational goals.
  • This is a US based remote position, with preference given to local New England based candidates who can be in office 1 day per week. This role will require a minimum monthly or quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA. #LI-JF1 #LI-Remote 

What We Offer: Meaningful Work, Fair Rewards, and Real Support

At Entrada Therapeutics, we understand that compensation and total rewards are a major consideration when exploring a new opportunity. We believe in transparency and equity and are committed to sharing salary ranges for every position, along with insight into our compensation philosophy, in accordance with certain state requirements in the United States and fostering a fair and open environment at the onset. #LI-JF1 #LI-Onsite 

But we also know it is more than just pay. When you join Entrada, you’ll be part of a mission-driven team with access to comprehensive health, dental and vision coverage; life and disability insurance; with a 401(k) match. We pride ourselves on offering competitive benefits that empower our employees and reflect the value of their contributions – offering paid, gender-inclusive parental leave, holistic support for your health and well-being, education reimbursement, discretionary time off and commuting benefits aligned to your working model. If you find yourself working from our office in Boston’s Seaport District, this puts you steps away from some of the best the city has to offer.

“Our approach to compensation is grounded in transparency, equity and performance for the unique contributions each person brings. At Entrada, we know that meaningful work deserves meaningful reward — and we view compensation as one way we show appreciation for the collaboration, curiosity and commitment that drive our mission forward.”

— Kerry Robert, SVP of People

The salary for this opportunity ranges from $169,000 - $194,000. The final base compensation offered will depend on several considerations which include but may not be limited to a candidate’s skills, competencies, experience and other job-related factors permitted by law. The final salary offered may fall outside of this range.

Equal Opportunity Employer

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law. 

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

Privacy Statement

Entrada Therapeutics, Inc. (the “Entrada,” “we,” “us,” or “our”) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.